| Friday, September 24th | |
| Three-Rivers West | |
| Mon-Rose @ Rockridge | 7:00 |
| Sherrard vs. Morrison | 7:00 |
| Three-Rivers East | |
| Kewanee vs. Princeton | 7:00 |
| Bureau Valley @ Sterling Newman | 7:00 |
| Lincoln Trail Conference | |
| United @ Stark County | 7:00 |
| Abingdon-Avon @ Annawan/Wethersfield | 7:00 |
| Prairieland Conference | |
| Macomb @ Farmington | 7:00 |
| Elmwood/Brimfield vs. West Hancock | 7:00 |
| South Fulton @ Havana | 7:00 |
| Illini West vs. Rushville/Industry | 7:00 |
| Western Big Six Conference | |
| Galesburg @ Quincy | 7:30 |
| Rock Island vs. United Township | 7:30 |
| Alleman vs. Moline | 7:30 |
| Geneseo vs. Sterling | 7:30 |
| Non-Conference | |
| Princeville @ Lewistown | 7:00 |
| 8-Man Football | |
| BPC vs. Galva | 7:00 |
| Peoria Heights vs. River Ridge | 7:00 |
| Saturday, September 25th | |
| Three-Rivers West | |
| Orion vs. Erie-Prophetstown | 1:00 |
| Three-Rivers East | |
| Spring Valley Hall @ Mendota | 2:00 |
| TRAC-Cross-Over | |
| Riverdale @ Peru St. Bede | 1:00 |
| Lincoln Trail Conference | |
| Knoxville @ Ridgewood | 1:00 |
| 8-Man Football | |
| West Central @ Aquin Catholic | 1:00 |
| West Prairie @ Pawnee | 2:00 |
